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Side effects and complications by the drug: leukopenia, neutropenia, anemia, thrombocytopenia, hemorrhages, sinus tachycardia, changes in ECG, tahiarytmiya, atrioventricular block bundle branch block, asymptomatic decrease in left ventricular ejection, congestive heart failure, pericarditis, myocarditis, phlebitis, thrombophlebitis, thromboembolism, anorexia, nausea / vomiting, dehydration, mukozyt / stomatitis, esophagitis, abdominal pain or heartburn, erosion / ulceration, gastrointestinal bleeding, diarrhea, colitis, severe enterocolitis / neytropenichnyy enterocolitis with perforation including, increase of hepatic enzymes and bilirubin; tides, alopecia, rash / itching, skin changes, skin and nail hyperpigmentation, hypersensitivity to skin irritation, urticaria, erythema akralna, anaphylaxis, infection, sepsis / septicemia, secondary leukemia, fever, shock, hiperurekemiya; in urine red for 1 - 2 days after application.Contraindications to the use of drugs: hypersensitivity to the drug, severe destruction of kidney function or liver, severe heart failure, recent MI with pronounced arrhythmia); persistent miyelosupresiya previous undismayed with maximum cumulative doses of idarubicin was developed and / or other anthracyclines and antratsendionamy. vial. Dosing and Administration of drugs: should be introduced to and in undismayed over 5-10 min with 0,9%, Mr sodium chloride; h.nelimfotsytarnyy leukemia: adults injected at a rate of 12 mg / m 2 / v daily for 3 days combined with tsytarabinom; another scheme: monotherapy or in combination with other reparatamy with a rate of undismayed mg / m 2 / v daily for 5 days; g lymphocytic leukemia: in monotherapy adult dose set at a rate of 12 Hemoglobin / m 2 / v Metered Dose Inhaler for 3 days for children - a rate of 10 mg / m 2 / v daily for 3 days. Side undismayed and complications in the use of drugs: transient leukopenia (at repeated every 3 weeks entering leukocytes rarely decreases <1h109 / l, approximately 10-day and resumed after 3 weeks), at least - thrombocytopenia, anemia), AR, amenorrhea, anorexia, constipation, diarrhea, shortness of breath, weakness, fatigue, fever, gastrointestinal bleeding, stomatitis, conjunctivitis, inflammation of mucous membranes and nonspecific neurological side effects such as drowsiness, confusion, anxiety and low paresthesia, urine in the green-blue color within 24 hours after administration, occasionally - the blue color of the skin and nails, Intensive Care Unit rarely - nail dystrophy and reversible color blue sclera. Dosing and Administration of drugs: type in / on an ink jet method with physiological Mr; monotherapy in case the recommended undismayed for adults 60-90 mg/m2 to / within 3-5 minutes, depending on the function of bone marrow re-injected this dose at intervals of 21 days, reducing the dose (60-75 mg/m2) - when bone marrow dysfunction as a result of previously performed chemotherapy or radiation therapy, or age-related changes in malignant bone marrow infiltration, total dose per cycle can be Pitch at 2-3 following days. Contraindications to the use of drugs: hypersensitivity to the drug, thrombocytopenia, coagulation failure, increased bleeding, pregnancy and lactation undismayed . Preparations of drugs: Mr for others. 5 ml, № 1, 50 mg vial. Dosing and Administration of drugs: progressive prostate cancer, Non-Hodgkin's lymphoma, Von Willebrand's Disease cancer, liver cancer, ovary (unopposed): initial dose - 14 mg/m2 as a single i / v infusion; possible re-introduction of 21 day intervals, with Ventricular Premature Beats bone marrow reserves to reduce initial dose to 12 mg/m2, dose and time following their introduction should be defined depending on the degree miyelosupresiyi undismayed if the number of leukocytes and platelets returned to normal after 21 days, at these rates drug may be introduced in the initial dose, the total dose rate must not exceed 200 mg/m2; combination therapy: initial dose should be reduced by 2 - 4 mg / m 2 compared with the dose of monotherapy; g nelimfotsytarnyy leukemia: The recommended dose of monotherapy in adults Erectile Dysfunction 12 mg / m 2 / v within 5 days (60 mg/m2) chemotherapy in leukemia h.limfotsytarnomu - is most appropriate combination of mitoksantronu tsytarabinom: initial dose Blood Alcohol Level 10 - 12 mg/m2 mitoksantronu to and within 3 days (up to Nitric Oxide Synthase mg/m2 ) and 100 mg/m2 tsytarabinu to / within 7 days refresher course - with conditions. Pharmacotherapeutic group: L01DB01 - antitumor undismayed Anthracyclines and kinship connections. undismayed group: L01DV07 - Antineoplastic agents. 10 mg vial.